Figure 3.

Meta-analysis of prediction models. Random-effect models were used to pool similar models reported in independent cohorts. For the HOSPITAL score, the discriminations for the HF and AMI samples were similar (0.65 and 0.64). For GRACE, the discriminations for the AMI and reinfarction samples were similar (0.77 and 0.74), and was higher for the HF sample (0.83). Only GRACE demonstrated adequate discrimination in external cohorts. AMI, acute myocardial infarction; CMS, Centers for Medicare and Medicaid Services; CF, heart failure. Abbreviations: CMS = Centers for Medicare and Medicaid Services; AMI = Acute Myocardial Infarction; HF = Heart Failure; HOSPITAL = Hemoglobin level, discharged from Oncology, Sodium level, Procedure during admission, Index admission Type, Admission, Length of stay; GRACE = Global Registry of Acute Coronary Events; LACE = length of stay (L), acuity of the admission (A), comorbidity of the patient (C) and emergency department use in the duration of 6 months before admission.