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. Author manuscript; available in PMC: 2021 Aug 18.
Published in final edited form as: J Alzheimers Dis. 2019;67(2):541–553. doi: 10.3233/JAD-180776

Fig. 1.

Fig. 1.

Exosomes derived from neuronally-differentiated, human induced pluripotent stem cells (NiPSCEs) contain human tau species. Representative NTA plot of averaged size/concentration for exosomes derived from tau-RD-LM-YFP conditioned media from induced pluripotent stem cells (NiPSCEs) (A). Non-exosome (non-exo) and exosomal (exo) fractions were probed against the human recombinant tau protein using MC-1 and PHF1 antibodies. Representative western blots demonstrate that MC-1 and PHF1 immunoreactive tau is only detected in the exosomal fraction derived from NiPSCEs. Exosome surface marker, Flotillin-1, was used as a loading control (B).