TABLE 8.

Distinct multiple organism/antibiotic resistance gene combinations detected by the BCID-GN and discrepancies with comparator methods (clinical samples)

Distinct codetection combinations detected by the BCID-GN panelb
1	2	3	ARG	No. of samples (no. discrepanta)
A. baumannii*	K. pneumoniae GP*	Pan GP*	CTX-M, OXA	1 (1)
A. baumannii	Pan GP			4 (0)
A. baumannii	Pan GP^		OXA	4 (1)
B. fragilis*	E. cloacae complex	Pan GP		1 (1)
B. fragilis*	E. coli			2 (1)
B. fragilis	Pan GP			1 (0)
Citrobacter	E. cloacae complex^			1 (1)
Citrobacter*	E. cloacae complex*	K. oxytoca		2 (2)
Citrobacter	E. coli			1 (0)
Citrobacter*	K. oxytoca			1 (1)
Citrobacter*	K. oxytoca	K. pneumoniae GP		1 (1)
Citrobacter	K. oxytoca*	K. pneumoniae GP		1 (1)
Citrobacter	K. pneumoniae GP			1 (0)
Citrobacter	K. pneumoniae GP	Pan GP	CTX-M	1 (0)
Citrobacter	M. morganii*	Pan GP		1 (1)
Citrobacter	P. mirabilis	Pan GP*		1 (1)
Citrobacter	Pan GP*			3 (2)
E. cloacae complex	E. coli	K. pneumoniae GP		1 (0)
E. cloacae complex	K. pneumoniae GP			1 (0)
E. cloacae complex	P. aeruginosa*	Pan GP		1 (1)
E. cloacae complex	Pan Candida*			1 (1)
E. cloacae complex	Pan Candida	Pan GP		1 (0)
E. cloacae complex	Pan GP^			4 (1)
E. coli	K. oxytoca*			3 (1)
E. coli	K. oxytoca	Pan GP		1 (0)
E. coli	K. pneumoniae GP			2 (0)
E. coli*	K. pneumoniae GP		CTX-M	1 (1)
E. coli	M. morganii			1 (0)
E. coli	P. mirabilis			3 (0)
E. coli	P. mirabilis	Pan GP		1 (0)
E. coli	Pan GP*			10 (3)
E. coli	Pan GP		CTX-M	1 (0)
Enterobacter ^	K. pneumoniae GP			1 (1)
Enterobacter	Pan Candida			1 (0)
Enterobacter	Pan GP			1 (0)
H. influenzae	N. meningitidis^	P. aeruginosa^		1 (1)
K. oxytoca	K. pneumoniae GP*			2 (1)
K. oxytoca	Pan GP*			4 (2)
K. oxytoca	S. marcescens*			2 (1)
K. pneumoniae GP	P. mirabilis			1 (0)
K. pneumoniae GP	Pan GP*			6 (1)
K. pneumoniae GP	Pan GP^		CTX-M, KPC	1 (1)
K. pneumoniae GP*	Pan GP	S. marcescens		1 (1)
K. pneumoniae GP	S. maltophilia			1 (0)
M. morganii	P. aeruginosa*	Pan GP		1 (1)
M. morganii	P. mirabilis			2 (0)
M. morganii	Pan GP	Proteus		1 (0)
P. aeruginosa	P. mirabilis	Pan GP		1 (0)
P. aeruginosa	Pan GP			2 (0)
P. mirabilis	Pan GP*			8 (2)
P. mirabilis	Pan GP		CTX-M	1 (0)
Pan Candida	Pan GP			2 (0)
Pan GP	S. maltophilia			1 (0)
Pan GP	S. marcescens			3 (0)

^aA discrepant organism/ARG is one that was detected by the BCID-GN but not by the comparator method(s) (i.e., false positive); 36/39 false-positive organisms were investigated using PCR/sequencing (3 Pan GP organisms were not tested). Of the 36 false-positive organisms tested, 32 were detected, 3 were not detected, and 1 was indeterminate.

^b*, Discordant false-positive organism confirmed present by PCR/sequencing; ^, discordant false-positive organism not confirmed present by PCR/sequencing.