Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 14;14:2469–2479. doi: 10.2147/JPR.S323588

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Du et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

Puerarin regulates the Sirt1/TGF-β1/Smad3 signaling axis in the CFA-induced pain model of the trigeminal nerve. Sirt1 mRNA and protein levels in the trigeminal ganglions were determined using RT-qPCR (A) and Western blotting (B), respectively. TGF-β1, Smad3 and phosphorylated Smad3 levels were measured using Western blot analysis (C and D). *P<0.05, CFA group compared with the control group; ^#P<0.05, CFA+Pue or CFA+Res groups compared with the CFA group.

Abbreviations: Sirt1, Sirtuin1; CFA, complete Freund’s adjuvant; RT-qPCR, reverse transcription-quantitative PCR.