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Puerarin inhibits inflammation in nerve cells. Following exposure of nerve cells to IL-1β (10 ng/mL) and TNF-α (50 ng/mL) or puerarin (100 μM), NLRP1, NLRP3, caspase-1, IL-1β, IL-8, IL-18, MCP-1 and CCL2 mRNA levels were determined using RT-qPCR. *P<0.05, IL-1β+TNF-α compared with the control group; $P<0.05, IL-1β+TNF-α compared with the IL-1β+TNF-α+puerarin group.
Abbreviation: RT-qPCR, reverse transcription-quantitative PCR.
