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. Author manuscript; available in PMC: 2021 Aug 18.
Published in final edited form as: J Lung Pulm Respir Res. 2020 Nov 17;7(4):85–91.

Figure 5.

Figure 5

The MAS receptor agonist AVE-0991 restores and increases the SP-C in cultured human primary AECs monolayers under hyperoxic conditions (95% oxygen). Human primary AECs were cultured on 6 well plates to sub-confluence as described in Methods and were then exposed to 95% O2 in the presence or absence of the MAS receptor agonist AVE0991. See Methods for details. Bars are the mean +/− S.E.M.; * p<0.001 AVE normoxia Vs DMSO normoxia, ** p<0.001 AVE hyperoxia vs DMSO normoxia, *** p<0.001 DMSO hyperoxia vs DMSO normoxia, **** p<0.001 AVE hyperoxia vs AVE normoxia, ***** p<0.001 AVE hyperoxia vs DMSO hyperoxia, ****** p<0.001 DMSO hyperoxia vs AVE normoxia using ANOVA Student-Newman-Keuls test, n=3.