Graphical Abstract.
Single cell evaluation of post-translational epigenetic encoding (SCEPTRE) uses expansion microscopy to combine DNA in situ labeling with immunofluorescence and quantify histone mark levels at individual loci within cells.
Single cell evaluation of post-translational epigenetic encoding (SCEPTRE) uses expansion microscopy to combine DNA in situ labeling with immunofluorescence and quantify histone mark levels at individual loci within cells.