Metabolite test | Treatment 1 | Treatment 2 |
---|---|---|
Glucose/pyruvate dependence | UK5099 | Etomoxir + BPTES + BCATci‐2 |
Glutamine dependence | BPTES | Etomoxir + UK5099 + BCATci‐2 |
Fatty acid dependence | Etomoxir | BPTES + UK5099 + BCATci‐2 |
BCAA dependence | BCATci‐2 | Etomoxir + UK5099 + BPTES |
Dependency (%) = [(Baseline OCR‐target inhibitor OCR) / (Baseline OCR‐all inhibitors OCR)] × 100%