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. 2021 Jun 27;8(16):2004993. doi: 10.1002/advs.202004993

Fuel Dependence

Metabolite test Treatment 1 Treatment 2
Glucose/pyruvate dependence UK5099 Etomoxir + BPTES + BCATci‐2
Glutamine dependence BPTES Etomoxir + UK5099 + BCATci‐2
Fatty acid dependence Etomoxir BPTES + UK5099 + BCATci‐2
BCAA dependence BCATci‐2 Etomoxir + UK5099 + BPTES

Dependency (%) = [(Baseline OCR‐target inhibitor OCR) / (Baseline OCR‐all inhibitors OCR)] × 100%