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. 2021 Jul 9;49(14):7839–7855. doi: 10.1093/nar/gkab580

Figure 3.

Figure 3.

Roles of non-canonical structures in cancer cells. Non-canonical structures control gene expression. Formation of a non-canonical structure in the promoter region inhibits polymerase binding. Formation of non-canonical structures in the coding regions of DNA and mRNA inhibits transcription and translation, respectively.