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. 2021 Jul 16;65(8):e00926-21. doi: 10.1128/AAC.00926-21

TABLE 3.

Enmetazobactam sigmoid Emax model parameters determined for the ESBL-producing isolates of K. pneumoniae used in this study

Subset of isolates IC50 (μg/ml)
γ
MICCemt() (μg/ml)
Range Median Range Median Range Median
Complete set of isolates (n = 84) 1.0 × 10−8 to 3.9 × 10−8 0.02 0.35 to 13.6 1.4 0.03 to 8.0 0.06
CTX-M-15-only producers (n = 64) 1.0 × 10−8 to 3.4 × 10−8 0.01 0.44 to 13.5 1.4 0.03 to 1.0 0.06
CTX-M-15+OXA-48 producers (n = 6) 2.5 × 10−6 to 3.9 × 10−6 0.01 0.35 to 3.6 1.1 0.03 to 8.0 0.1