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. 2021 Aug 14;14:1033–1043. doi: 10.2147/JAA.S316250

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© 2021 Chen et al.

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Successful establishment of murine asthma model. (A) Protocol of murine asthma model by using OVA. (B) The number of leukocytes, neutrophils, eosinophils, lymphocytes and monocytes in BALF of murine asthma group and control group. (C) The levels of IgE, IFNγ and IL-5 in BALF were determined by Elisa analysis. (D) HE (haematoxylin and eosin) and PAS (periodic acid-Schiff stain) analysis of lung tissues in murine asthma group and control group, and histopathology score (PA) and periodic acid-Schiff stain score (PAS). The study was repeated for three times. **P<0.01; ***P<0.001, ****P<0.0001.