. 2021 Jun 9;35(8):e23871. doi: 10.1002/jcla.23871

TABLE 1.

Demographic and clinical features of enrolled participants

Clinical features	TB patients	TB‐DCs	p ^a	HCs	p ^b
Total	60	24	/	48	/
Gender, male	35 (58.3%)	13 (54.2%)	0.67	23 (47.9%)	0.24
Age (years)	37.08 ± 18.153	60.33 ± 12.506	0.007	39.77 ± 11.265	0.35
Radiologic pathology^c	56 (93.3%)	24 (100.0%)	0.267	0	< 0.001
Fever	13 (21.7%)	5 (20.8%)	0.32	0	< 0.001
Night sweat	7 (11.7%)	0	0.08	0	< 0.001
Coughing	35 (58.3%)	15 (62.5%)	0.79	0	< 0.001
Expectoration	29 (48.3%)	11 (45.8%)	0.78	0	< 0.001
Hemoptysis	10 (16.7%)	2 (8.3%)	0.31	0	< 0.001
Fatigue	13 (21.7%)	3 (12.5%)	0.32	0	< 0.001
Weight loss	5 (8.3%)	1 (4.2%)	0.49	0	0.04
Erythrocytes (×10¹²/L)	4.34 ± 0.58	4.24 ± 0.44	0.45	4.66 ± 0.38	< 0.001
Hemoglobin (g/L)	126.40 ± 18.77	125.10 ± 18.27	0.78	144.15 ± 14.24	< 0.001
Hematocrit	0.39 (0.20–0.51)	0.39 (0.27–0.46)	0.94	0.43 (0.36–0.50)	< 0.001
Platelets (×10⁹/L)	272 ± 87.91	214.92 ± 80.99	0.01	237.06 ± 46.54	0.01
Leukocyte (×10⁹/L)	6.41 (2.72–16.82)	6.14 (3.42–11)	0.52	5.77 (4.01–9)	0.15
TBIL (µmol/L)	14.42 (5.34–196.18)	9.47 (3.70–28.60)	0.38	10.79 (3.90–20.70)	0.28
ALT (U/L)	23.93 (2–306)	22.58 (7–72)	0.04	17.10 (6–38)	0.04
AST (U/L)	20.27 (6–90)	25.75 (10–125)	0.19	18.56 (11–32)	0.17
Albumin (g/L)	38.52 ± 6.14	40.69 ± 6.81	0.17	46.96 ± 3.02	< 0.001
Urea (mmol/L)	4.10 ± 1.32	5.05 ± 1.53	0.01	4.75 ± 1.24	0.01
Creatinine (µmol/L)	60.62 ± 16.14	67.12 ± 20.80	0.14	70.60 ± 13.36	< 0.001
UA (µmol/L)	358.16 (178–710)	244.33 (168–339)	< 0.001	296.54 (170–454)	0.08
ESR	27.75 (2–117)	19.47 (2–63)	0.59	5.50 (2–8)	0.29
CRP (mg/L)	16.85 (0.25–177.91)	18.43 (1–244)	0.13	0.36 (0.24–0.62)	< 0.001
Glucose (mmol/L)	5.29 (3.47–20.47)	5.01 (3.63–9.75)	0.95	4.87 (4.10–5.74)	0.10
MCV (fl)	88.99 (77.70–103.40)	90.91 (60.60–100.40)	0.06	92.36 (84.90–100)	< 0.001
MCH (pg)	29.20 (23.30–34.20)	29.50 (18–32)	0.14	30.93 (26.90–34.20)	< 0.001
MCHC (g/L)	327.05 ± 11.62	323.80 ± 9.11	0.23	334.93 ± 9.04	< 0.001
RDW (×10⁹/L)	13.19 (11–20)	13.45 (10.10–17.20)	0.04	12.79 (11.40–13.80)	0.84
MPV (fl)	10.57 (8.20–12.90)	9.54 (0.40–16.80)	0.01	9.31 (7.20–13.10)	< 0.001
Plateletcrit	0.28 (0.10–0.50)	0.84 (0.11–15.50)	< 0.001	0.22 (0.13–0.30)	< 0.001
PDW (fl)	12.51 (8.70–19.30)	16.50 (15.50–17.50)	< 0.001	16.21 (15.53–17.11)	< 0.001
GGT (U/L)	32.89 (8–292)	26.50 (8–72)	0.68	19.98 (6–48)	0.03
ALP (U/L)	90.58 (49–351)	75.29 (36–125)	0.10	67.04 (32–109)	< 0.001
DBIL (µmol/L)	5.86 (1–141)	4.35 (1.70–9.70)	0.04	4.81 (1.90–8.30)	< 0.001
LDH (U/L)	182.57 (129–303)	217.38 (10–431)	0.03	168.80 (138–204)	0.56
T‐CHO (mmol/L)	4 ± 0.91	4.03 ± 0.92	0.91	4.02 ± 0.61	0.23
Triglycerides (mmol/L)	1.13 (0.41–2.94)	1.25 (0.52–4.61)	0.62	1.02 (0.45–1.78)	0.72
HDL (mmol/L)	1.03 ± 0.31	1.21 ± 0.34	0.05	1.42 ± 0.88	0.01
LDL (mmol/L)	2.70 ± 0.79	2.46 ± 0.75	0.26	2.63 ± 0.55	0.61

Abbreviations: ALP, alkaline phosphatase; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CRP, C‐reactive protein; DBIL, direct bilirubin; ESR, erythrocyte sedimentation rate; GGT, γ‐glutamyl transpeptidase; HCs, healthy controls; HDL, high‐density lipoprotein; LDH, lactate dehydrogenase; LDL, low‐density lipoprotein; MCH, mean corpuscular hemoglobin; MCHC, mean red blood cell hemoglobin concentration; MCV, mean red blood cell volume; MPV, mean platelet volume; PDW, platelet distribution width; RDW, red blood cell distribution width; TB‐DCs, non‐TB disease controls; TBIL, total bilirubin; T‐CHO, total cholesterol; UA, uric acid.

^{^a}

p Value for the comparison of TB patients and TB‐DCs.

^{^b}

p Value for the comparison of TB patients and HCs.

^{^c}

Radiologic pathology refers to abnormal chest imaging, including at least one of the signs: shadow, calcification, cavity, fibrosis, and pleural effusion.