Table 2.
Sham | CHF | |||
---|---|---|---|---|
Cont | Salusin-β | Cont | Salusin-β | |
LVEDD, mm | 7.12 ± 0.23 | 6.76 ± 0.43 | 11.36 ± 0.21† | 9.24 ± 0.28∗† |
LVESD, mm | 4.65 ± 0.13 | 3.49 ± 0.30 | 9.27 ± 0.40† | 7.86 ± 0.25∗† |
IVSd, mm | 1.79 ± 0.05 | 1.70 ± 0.10 | 1.28 ± 0.13 | 1.40 ± 0.19 |
IVSs, mm | 2.86 ± 0.13 | 2.93 ± 0.14 | 1.86 ± 0.26 | 1.76 ± 0.26 |
LVPWd, mm | 1.86 ± 0.03 | 1.97 ± 0.12 | 1.63 ± 0.10 | 2.02 ± 0.07 |
LVPWs, mm | 3.21 ± 0.11 | 3.08 ± 0.11 | 2.46 ± 0.30† | 2.97 ± 0.08∗ |
FS, % | 43.41 ± 1.24 | 48.54 ± 1.90 | 17.84 ± 1.02† | 25.52 ± 2.01∗† |
EF, % | 72.60 ± 1.33 | 78.59 ± 1.83 | 34.73 ± 1.78† | 47.55 ± 3.30∗† |
LV mass (g) | 1.19 ± 0.08 | 1.03 ± 0.17 | 1.55 ± 0.10† | 1.53 ± 0.08† |
LV mass/BW (mg/g) | 2.81 ± 0.33 | 2.52 ± 0.47 | 3.73 ± 0.47† | 3.66 ± 0.32† |
LVEDD: left ventricular end-diastolic diameter; LVESD: left ventricular end-systolic diameter; IVSd: interventricular septal thickness in diastole; IVSs: interventricular septal thickness in systole; LVPWd: left ventricular posterior wall thickness in diastole; LVPWs: left ventricular posterior wall thickness in systole; FS: fractional shortening; EF: ejection fraction; LV: left ventricular; BW: body weight. Values are mean ± SE. ∗P < 0.05 vs. Cont-shRNA. †P < 0.05 vs. Sham. n = 6 for each group.