Table 1.
Effect Z. jujuba extract on the latency to reach the platform during the acquisition phase in the Morris water maze.
| Treatment | Day 1 lat. (s) | Day 2 lat. (s) | Day 3 lat. (s) | Day 4 lat. (s) |
|---|---|---|---|---|
| DW + DW | 21.3 ± 4.4 | 8.3 ± 0.8 | 6.9 ± 0.5 | 5.9 ± 0.2 |
| SCO + DW | 29.3 ± 3.5 | 15.0 ± 2.0 | 14.1 ± 2.2 | 14.5 ± 2.7c |
| SCO + DZ | 24.7 ± 2.2 | 13.3 ± 2.6 | 12.8 ± 2.5 | 6.1 ± 1.1∗∗ |
| SCO + TA | 51.7 ± 4.3 | 10.6 ± 1.8 | 9.8 ± 1.5 | 10.9 ± 1.4 |
| SCO + E29 | 38.8 ± 2.1 | 9.8 ± 0.9 | 6.2 ± 0.8 | 5.2 ± 0.4∗∗∗ |
| SCO + E57 | 36.9 ± 6.7 | 6.9 ± 0.7 | 8.8 ± 0.9 | 7.2 ± 0.7∗∗ |
| SCO + E114 | 27.2 ± 3.4 | 6.7 ± 1.5 | 7.4 ± 0.6 | 6.0 ± 0.7∗∗∗ |
Each value represents the average ± SEM; n = 7. cp < 0.001vs. normal control. ∗∗p < 0.01; ∗∗∗p < 0.001vs. negative control. s: second; lat.: latency time; DW: distilled water (10 ml/kg); SCO: scopolamine (1 mg/kg); DZ: donepezil (1.2 mg/kg); TA: tacrine (10 mg/kg); E29, E57, and E114: aqueous extracts of Z. jujuba at respective doses of 29, 57, and 114 mg/kg. DW + DW: normal control group; SCO + DW: negative control group; SCO + DZ: positive control group with donepezil; SCO + TA: positive control group treated with tacrine; SCO + E29-E114: test groups treated with Z. jujuba extract.