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. 2021 Aug 10;2021:5577163. doi: 10.1155/2021/5577163

Table 2.

Effect of Z. jujuba extract on some oxidative stress markers in the hippocampus.

Treatment Oxidative stress markers in the hippocampus
GSH (μmol/g) MDA (mmol/g) SOD (unit/min/g) Nitrite (mmol/g) Total protein (μg/ml)
DW + DW 690.1 ± 48.3 17.1 ± 1.2 14.4 ± 0.8 144.1 ± 1.7 1751.3 ± 24.1
SCO + DW 316.4 ± 18.9c 64.6 ± 3.4c 146.1 ± 14.3c 532.4 ± 3.4c 450.8 ± 13.2c
SCO + DZ 322.1 ± 23.5 27.0 ± 1.6∗∗∗ 201.3 ± 19.4∗∗∗ 320.9 ± 3.6∗∗∗ 1289.5 ± 17.8∗∗∗
SCO + TA 720.1 ± 85.6 40.5 ± 7.4∗∗∗ 743.6 ± 34.9∗∗∗ 409.2 ± 2.2∗∗∗ 1176.2 ± 34.4∗∗∗
SCO + E29 561.9 ± 30.3 16.3 ± 1.3∗∗∗ 191.1 ± 15.5∗∗∗ 332.8 ± 2.2∗∗∗ 1139.9 ± 39.3∗∗∗
SCO + E57 319.4 ± 11.5 17.9 ± 1.1∗∗∗ 187.9 ± 10.8∗∗∗ 331.2 ± 3.8∗∗∗ 1352.3 ± 26.4∗∗∗
SCO + 114 544.3 ± 33.2 28.3 ± 1.8∗∗∗ 260.4 ± 13.2∗∗∗ 327.2 ± 2.6∗∗∗ 1466.3 ± 21.1∗∗∗

Each value represents the average ± SEM; n = 7. cp < 0.001vs. normal control. p < 0.05; ∗∗∗p < 0.001vs. negative control; DW: distilled water (10 ml/kg); SCO: scopolamine (1 mg/kg); DZ: donepezil (1.2 mg/kg); TA: tacrine (10 mg/kg); E29, E57, and E114: aqueous extract of Z. jujuba at respective doses of 29, 57, and 114 mg/kg. DW + DW: normal control group; SCO + DW: negative control group; SCO + DZ: positive control group treated with donepezil; SCO + TA: positive control group with tacrine; SCO + E29-E114: test groups treated with Z. jujuba extract; GSH: reduced glutathione; MDA: malondialdehyde; SOD: superoxide dismutase.