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. 2021 Aug 10;2021:5577163. doi: 10.1155/2021/5577163

Table 3.

Effect of Z. jujuba extract on some oxidative stress markers in the prefrontal cortex.

Treatment Oxidative stress markers in the prefrontal cortex
GSH (μmol/g) MDA (mmol/g) SOD (unit/min/g) Nitrite (mmol/g) Total protein (μg/ml)
DW + DW 1134.1 ± 102.4 4.5 ± 0.5 61.3 ± 5.1 169.6 ± 1.7 2170.9 ± 36.1
SCO + DW 232.6 ± 33.7c 13.3 ± 2.3c 212.6 ± 373.2c 613.6 ± 2.8c 331.6 ± 32.2c
SCO + DZ 487.3 ± 49.2 7.2 ± 2.6 126.5 ± 16.6∗∗∗ 402.7 ± 2.4∗∗∗ 1202.2 ± 33.9∗∗∗
SCO + TA 720.9 ± 75.2∗∗ 6.2 ± 1.1∗∗ 59.4 ± 7.3∗∗∗ 530.4 ± 3.2∗∗∗ 1404.1 ± 25.1∗∗∗
SCO + E29 848.1 ± 87.9∗∗∗ 9.5 ± 0.7 271.8 ± 24.1∗∗∗ 370.4 ± 3.5∗∗∗ 958.6 ± 28.4∗∗∗
SCO + E57 710.4 ± 79.9∗∗ 9.5 ± 1.2 395.1 ± 48.3∗∗∗ 366.4 ± 2.8∗∗∗ 865.3 ± 26.7∗∗∗
SCO + 114 538.1 ± 56.9 5.3 ± 0.5∗∗ 321.5 ± 27.5∗∗∗ 425.2 ± 1.1∗∗∗ 683.9 ± 32.4∗∗∗

Each value represents the average ± SEM; n = 7. cp < 0.001vs. normal control. p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001vs. negative control; DW: distilled water (10 ml/kg); SCO: scopolamine (1 mg/kg); DZ: donepezil (1.2 mg/kg); TA: tacrine (10 mg/kg); E29, E57, and E114: aqueous extract of Z. jujuba at respective doses of 29, 57, and 114 mg/kg. DW + DW: normal control group; SCO + DW: negative control group; SCO + DZ: positive control group with donepezil; SCO + TA: positive control group treated with tacrine; SCO + E29-E114: test groups treated with Z. jujuba extract; GSH: reduced glutathione; MDA: malondialdehyde; SOD: superoxide dismutase.