Table 2.
Change in ocular parameters at different timepoints.
0.01% A (n = 50) | 0.01% A + AAS (n = 50) | P a | P b | P c | |
---|---|---|---|---|---|
Spherical equivalent (D) d | |||||
Change at 1 m | −0.09 ± 0.03 | −0.04 ± 0.03 | 0.23 | <0.001∗ | 0.36 |
Change at 3 m | −0.20 ± 0.03 | −0.13 ± 0.03 | 0.12 | ||
Change at 6 m | −0.38 ± 0.04 | −0.25 ± 0.04 | 0.02∗ | ||
| |||||
Axial length (mm) d | |||||
Change at 1 m | 0.04 ± 0.04 | 0.03 ± 0.04 | 0.37 | <0.001∗ | 0.46 |
Change at 3 m | 0.12 ± 0.05 | 0.10 ± 0.05 | 0.28 | ||
Change at 6 m | 0.23 ± 0.05 | 0.20 ± 0.05 | 0.15 | ||
| |||||
Subfoveal choroidal thickness (μm) | |||||
Change at 1 m | −0.74 ± 2.55 | 2.09 ± 2.71 | 0.36 | 0.033∗ | 0.59 |
Change at 3 m | −3.15 ± 3.00 | −1.57 ± 2.82 | 0.61 | ||
Change at 6 m | −9.18 ± 2.76 | −7.92 ± 2.92 | 0.55 | ||
| |||||
Average choroidal thickness (μm) | |||||
Change at 1 m | −1.27 ± 1.60 | 0.04 ± 1.68 | 0.79 | ||
Change at 3 m | −2.99 ± 1.87 | −0.67 ± 1.69 | 0.21 | 0.039∗ | 0.61 |
Change at 6 m | −4.75 ± 2.04 | −3.00 ± 1.70 | 0.45 | ||
| |||||
Anterior chamber depth (mm) | |||||
Change at 1 m | 0.01 ± 0.01 | 0.01 ± 0.00 | 0.76 | ||
Change at 3 m | 0.01 ± 0.01 | 0.02 ± 0.00 | 0.82 | <0.001∗ | 0.48 |
Change at 6 m | 0.03 ± 0.01 | 0.03 ± 0.01 | 0.28 | ||
| |||||
Intraocular pressure (mmHg) | |||||
Change at 1 m | −0.27 ± 0.32 | 0.19 ± 0.29 | 0.33 | ||
Change at 3 m | −0.11 ± 0.34 | 0.01 ± 0.33 | 0.80 | 0.17 | 0.18 |
Change at 6 m | 0.93 ± 0.39 | 0.51 ± 0.37 | 0.48 |
Values are expressed as means ± standard error. aP value tests for group difference; bP value tests for time; cP value tests for the interaction between treatment and time; dadjusted for age, sex, baseline spherical equivalent, number of myopic parents, and outdoor time. ∗Significant at 0.05.