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. Author manuscript; available in PMC: 2022 Aug 1.
Published in final edited form as: Schizophr Res. 2021 Feb 23;234:87–93. doi: 10.1016/j.schres.2021.02.001

Table 4.

Odds ratios for C4 haplogroup associations with PANSS and RBANS scores

PANSS positive PANSS negative RBANS
OR (95th%CI) p OR (95th%CI) p OR (95th%CI) p
HTZ HMZ HTZ HMZ HTZ HMZ
Control
 AL-BS NA NA NA NA NS 0.94
(0.89–1.00)
0.03
 AL-BL NA NA NA NA NS 1.07
(1.00–1.14)
0.02
 BS NA NA NA NA NS NA
 AL NA NA NA NA NS NA
 AL-AL NA NA NA NA NS NA
Schizophrenia
 AL-BS NS NS NS NS NS NS
 AL-BL NS NS NS NS NS NS
 BS NS 0.54
(0.33–0.88)
0.0001		 NS NS NS 0.82
0.76–0.90
0.0001
 AL NS NS 1.24
(1.09–1.40)
0.0001		 8.62
(1.48–50.34)
0.0001		 NS 0.68
(0.55–0.83)
0.0001
 AL-AL 0.92
(0.85–1.00)
0.0001		 NS NS NS NS NS

OR – odds ratio; CI – confidence interval; p – p-value; HTZ – heterozygote; HMZ – homozygote; NS - not statistically significant at p<0.05; NA - not applicable (due to absence of homozygotes in the control group); PANSS positive refers to positive psychiatric symptoms; PANSS negative refers to negative psychiatric symptoms.

Comparison is HTZ and HMZ relative to absence of haplotype.