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Epitopes recognized by anti-SARS-CoV-2 mAbs
mAbs were tested for inhibition of VSV-EGFP-SARS-CoV-2-S neutralization escape mutants.
(A) The “+” symbol indicates resistance to neutralization when a mutation at the indicated residue number is present.
(B–F) Residues from (A) are highlighted on the RBD structure (PDB: 6M0J) in red, orange, green, or cyan for mAbs from group A, B, C, or D, respectively, and indicated. Residues that engage hACE2 are highlighted in tan.
