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. Author manuscript; available in PMC: 2022 Aug 10.
Published in final edited form as: Circ Heart Fail. 2021 Aug 10;14(8):e008170. doi: 10.1161/CIRCHEARTFAILURE.120.008170

Figure 4. NAD+ redox imbalance exacerbates diabetic cardiomyopathy, independent on tissue fibrosis.

Figure 4.

(A) Collagen levels of diabetic mouse hearts were quantified by trichrome staining. (B) Cardiomyocyte sizes of these hearts were quantified. N=4-6. Transcript expression levels of fibrosis-related genes were quantified by qPCR analyses. (C) Adamts proteinases and integrins, and (D) laminins and MMPs in diabetic control and diabetic cKO male hearts were measured. N=3.