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. Author manuscript; available in PMC: 2022 Feb 15.
Published in final edited form as: Cancer Res. 2021 Jun 24;81(16):4275–4289. doi: 10.1158/0008-5472.CAN-21-0198

Figure 4. MAOA promotes nuclear YAP1-AR interaction for enhanced AR transcriptional activity.

Figure 4.

(A) Determination of PSA-luc activity by R1881 (10 nM, 24 hrs) ± verteporfin (5 μM, 24 hrs) in the indicated control and MAOA-KD cells (n=3). (B) qPCR of PSA and PLZF by verteporfin (5 μM, 24 hrs) in the indicated control and MAOA-KD cells (n=3). (C) Representative PLA staining of YAP1-AR interaction in the indicated cell pairs. AR antibody incubation alone served as negative control. Scale bars: 20 μm. (D) Quantitation of nuclear YAP1-AR interaction by per-nucleus fluorescence intensity in the indicated cell pairs. Data represent the mean ± SEM. *p<0.05, **p<0.01; ns, not significant.