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Embryo loss during development.
| Genotype | Pregs | CL (Avg) | Embryos (Avg) | % embryo loss |
|---|---|---|---|---|
| WT | 6 | 59 (9.8) | 57 (9.5) | 3.4 |
| Mlh1E268G | 6 | 58 (9.7) | 38 (6.3) | 34.5 |
| Mlh1K618E | 3 | 37 (12.3) | 29 (9.7) | 21.6 |
| Mlh1K618T | 5 | 46 (9.2) | 39 (7.8) | 15.2 |
| Mlh1V326A | 4 | 35 (8.8) | 31 (7.8) | 11.4 |
| Mlh1V716M | 3 | 33 (11) | 23 (7.7) | 30.3 |
All mutant genotypes are homozygous. Pregs pregnancies dissected, CL Corpora lutea, Avg average. The embryos counted were viable when dissected at E13.5. The % embryo loss = (#CL-#embryos)/#CL * 100.
