Figure 2.

Female and male Foxp2^+/– mice display decreased time spent investigating different odors. Mice were exposed to different odors (e.g. neutral: water; non-social: peanut butter; and social: female or male urine) three times each for 2 min (with intervals of 2 min between odor exposure). Both female and male Foxp2^+/– mice spent significantly less time sniffing a non-social motivating odor (peanut) than control mice (A,B). Additionally, female Foxp2^+/– mice spent significantly less time sniffing both a neutral odor and a social motivating odor (male urine) (B). The experiment was repeated in two different cohorts (Foxp2^+/– n = 13, ctr n = 12; p* ≤ 0.05; p** ≤ 0.01).