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. 2021 Aug 5;15:706079. doi: 10.3389/fnbeh.2021.706079

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Copyright © 2021 Herrero, Wang, Hernandez-Pineda, Banerjee, Matos, Goodrich, Panigrahi, Smith and Corbin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Decreased male territorial aggression in Foxp2^+/– mice. An intruder C57BL/6J male was introduced into the home-cage of either a Foxp2^+/– or ctr male for 10 min. Male Foxp2^+/– mice displayed a significant decrease in both the number and duration of attacks compared to ctr (A,C). However, male Foxp2^+/– mice did not display any differences in latency to first attack or social exploration, or difference in latency to first attack or social exploration compared to ctr (B,D,E). The total duration of social exploration was also unchanged (F) (Foxp2^+/– n = 10, ctr n = 10). p** ≤ 0.01.