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. 2021 Aug 5;15:706079. doi: 10.3389/fnbeh.2021.706079

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Copyright © 2021 Herrero, Wang, Hernandez-Pineda, Banerjee, Matos, Goodrich, Panigrahi, Smith and Corbin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Heatmaps of differentially expressed proteins in the MeA of female and male Foxp2^+/– mice. Pooled microdissected MeA tissue from thee brains was run in duplicate. Ratios for each duplicate are shown in the x-axis and protein names (symbols) of differentially expressed proteins are displayed on the y-axis on the right. Panels (A–C) show proteins significantly upregulated (red) or downregulated (green) in three comparisons: Foxp2^+/– female vs. ctr female (mtF/ctrF) (A), Foxp2^+/– male vs. ctr male (mtM/ctrM) (B), Foxp2^+/– female vs. Foxp2^+/– male (mtF/mtM) (C) (Log2 fold change ≥ |1.11|). Proteins were clustered based on similarity of expression between the experimental and control groups, which is indicated by the dendrogram. The color key and histogram panel indicates the Z-scores of expression and the expression counts. See Supplementary Table 1 for a full list of altered proteins in each comparison.