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MPA trough concentrations
| Cohort 1 MPA monotherapy |
Cohort 2 MPA + ldCM |
Total | |
|---|---|---|---|
| Mean MPA (ng/ml) | 14.5 ± 8.9 | 42.1 ± 66.4 | 26.7 ± 45.6 |
| Cycle 1, Day 10–14 | |||
| Patients requiring dose escalation | 14/14 | 13/16 | 27/20 |
| Mean MPA (ng/ml) | 52.6 ± 65.3 | 66.4 ± 71.5 | 58.6 ± 66.8 |
| Cycle 2, Day 1 | |||
| Patients achieving MPA ≥ 50 ng/ml at any time | 10/14 | 7/16 | 17/30 |
