Table 3.
Early treatment response as determined by gadolinium-enhanced MRI 1 month after treatment and 6-month PFS and median OS
| Response | All patients | rGBM | rAA | Median PFS (mo) | Median OS (mo) |
|---|---|---|---|---|---|
| Partial response | 1 (10%) | 1 (14%) | 0 (0%) | 21.8 | 27.5 |
| Stable disease | 6 (60%) | 4 (57%) | 2 (66%) | 9.5 | 13.7 |
| Progressive disease | 3 (30%) | 2 (29%) | 1 (33%) | 2.5 | 6.3 |
| 6-month PFS | 5 (45%) | 4 (50%) | 1 (33%) | ||
| Median OS (mo) | 11.0 | 12.7 | 11.0 |
Abbreviations: MRI = magnetic resonance imaging; OS = overall survival; PFS = progression-free survival; rAA = recurrent anaplastic astrocytoma; rGBM = recurrent glioblastoma multiforme