Table 5.
Combined Genotype Association with Disease Risk
| TUG1 | MIAT | MALAT1 | SENCR | DM | DR | Cum Freq | Adjusted OR (95% CI)* | P-value | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | G | T | C | C | 0.218 | 0.134 | 0.154 | 1.00 | – |
| 2 | G | T | T | C | 0.080 | 0.103 | 0.262 | 1.26 (0.23–6.80) | 0.79 |
| 3 | A | T | C | T | 0.097 | 0.105 | 0.359 | 0.51 (0.08–3.44) | 0.49 |
| 4 | A | C | C | C | 0.044 | 0.104 | 0.446 | 2.97 (0.43–20.4) | 0.27 |
| 5 | G | T | C | T | 0.066 | 0.070 | 0.528 | 17.1 (1.9–149.8) | 0.012 |
| 6 | G | T | T | T | 0.130 | 0.057 | 0.608 | 0.70 (0.17–3.0) | 0.64 |
| 7 | G | C | T | C | 0.035 | 0.083 | 0.670 | 7.7 (0.75–79.2) | 0.088 |
| 8 | G | C | C | C | 0.042 | 0.069 | 0.731 | 20.9 (2.07–212) | 0.012 |
| 9 | G | C | C | T | 0.018 | 0.093 | 0.790 | 1.03 (0.09–11.9) | 0.98 |
| 10 | A | T | T | C | 0.074 | 0.034 | 0.843 | 0.63 (0.08–5.30) | 0.68 |
| 11 | G | C | T | T | 0.039 | 0.028 | 0.880 | 4.31 (0.37–50.2) | 0.25 |
| 12 | A | T | T | T | 0.040 | 0.031 | 0.915 | 0.38 (0.03–5.19) | 0.47 |
| 13 | A | C | T | T | 0.018 | 0.026 | 0.941 | 0.71 (0.04–11.2) | 0.81 |
| 14 | A | T | C | C | 0.027 | 0.020 | 0.967 | 4.39 (0.25–76.5) | 0.31 |
| 15 | A | C | C | T | 0.012 | 0.026 | 0.988 | 1.92 (0.13–28.3) | 0.64 |
| 16 | A | C | T | C | 0.052 | 0.000 | 1.0 | 0.45 (0.01–22.6) | 0.69 |
Notes: Global haplotype association P-value: 0.04. *Adjusted OR by age, sex, disease duration, hypoglycemic treatment, and hypertension were estimated. Bold values indicate significance at P-value < 0.05.
Abbreviations: DM, diabetes without diabetic retinopathy; DR, diabetic retinopathy; Cum Freq, cumulative frequency; OR, odds ratio; CI, confidence interval.