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. 2021 Aug 5;9:715037. doi: 10.3389/fcell.2021.715037

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Copyright © 2021 Wang and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Model of the kinocilium and its cross section. The kinocilium shows a 9 + 2 axoneme pattern with typical motile cilium structures such as outer dynein arms and radial spokes. However, a lack of inner dynein arms renders the lack of motor function. After the kinocilium degenerates, stereocilia mediate the entire mechano-electrical transduction (MET) process. When sound waves are transmitted to the cochlea, the shearing motion caused by lymph flow drives the passive swing of the hair bundle and sound signal processing.