Skip to main content
. 2021 Feb 8;162(9):2376–2385. doi: 10.1097/j.pain.0000000000002223

Table 4.

Baseline neurophysiological (nociceptive withdrawal reflex) parameters and psychophysical variables in the 2 study groups.

MIG group HC group P
RTh (mA) 16.5 ± 6.3 13.7 ± 6.1 F1,41 2.238; P = 0.142
Latency (ms) 107.7 ± 14.8 105.2 ± 15.2 F1,41 0.299; P = 0.587
Area (mV × ms) 2255.1 ± 1066.6 2114.7 ± 1220.7 F1,41 0.162; P = 0.690
VAS-RTh 6.2 ± 2.3 4.4 ± 1.7 F 1,41 7.321; P = 0.010
TST (mA) 11.5 ± 5.4 9.3 ± 4.1 F1,41 2.157; P = 0.150
VAS-TST-1 5.4 ± 2.1 3.3 ± 1.3 F 1,41 14.132; P = 0.001
VAS-TST-5 5.9 ± 2.5 3.6 ± 1.4 F 1,41 12.881; P = 0.001

MIG group: subjects with episodic migraine (n = 24); HC group: healthy controls (n = 19). RTh: single stimulus reflex threshold of the nociceptive withdrawal reflex (NWR); Area: area under the curve (mV*ms) of the NWR at RTh; VAS-RTh: pain perception as rated on a 0- to 10-point visual analogue scale at RTh; TST: temporal summation threshold of the NWR; VAS-TST-1 and VAS-TST-5: subjective pain perception of the first and fifth stimulus of the TST according to a 0- to 10-point visual analogue scale. In bold: statistically significant comparisons.

HC, healthy controls; MIG, migraine; RTh, reflex threshold; TST, temporal summation threshold; VAS, visual analogue scale.