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. 2021 Aug 5;59:339–350. doi: 10.1016/j.breast.2021.07.019

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© 2021 The Authors. Published by Elsevier Ltd.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 5 — HER2 protein levels detected by immunohistochemistry and ERBB2 mRNA levels according to HER2 IHC status.Legend. Representative pathological images of cHER2+ and cHER2-negative tumors courtesy of the Hospital Clinic of Barcelona Pathology Department and ERBB2 mRNA expression levels (log2 values) across HER2 IHC categories, as observed in 146 metastatic samples analyzed at the Translational Genomics and Targeted Therapies in Solid Tumors laboratory at IDIBAPS. HER2 protein and mRNA levels increase from left to right. HER2+: HER2-positive; IHC immunohistochemistry.