Table. Demographic and Clinical Characteristics of Patients at the Time of Listing.
| Variable | No. (%) | P value | ||
|---|---|---|---|---|
| Total (N = 1289) | Women (n = 459) | Men (n = 830) | ||
| Age, mean (SD), y | 56.1 (10.0) | 55.7 (10.6) | 56.3 (9.7) | .71 |
| Height, mean (SD), cm | 169.5 (9.5) | 161.6 (7.3) | 173.9 (7.7) | .001 |
| Weight, mean (SD), kg | 79.7 (18.6) | 71.2 (16.4) | 84.3 (18.1) | .001 |
| BMI, mean (SD)a | 27.6 (5.6) | 27.3 (6.1) | 27.8 (5.3) | .02 |
| Etiology of liver disease | ||||
| Alcoholic liver disease | 288 (22) | 72 (16) | 216 (26) | <.001 |
| Hepatitis C | 277 (22) | 75 (16) | 202 (24) | <.001 |
| Nonalcoholic fatty liver disease | 204 (16) | 85 (19) | 119 (14) | .049 |
| Primary sclerosing cholangitis | 89 (7) | 31 (7) | 58 (7) | .87 |
| Hepatitis B | 65 (5) | 13 (3) | 52 (7) | .007 |
| Primary biliary cholangitis | 64 (5) | 58 (13) | 6 (1) | <.001 |
| Autoimmune hepatitis | 54 (4) | 39 (9) | 15(2) | <.001 |
| Cryptogenic/unknown | 41 (3) | 12 (3) | 29 (4) | .39 |
| Hepatocellular carcinoma (listed without exception points) | 100 (8) | 26 (6) | 74 (9) | .04 |
| Miscellaneous | 107 (8) | 48 (11) | 59 (5) | .09 |
| MELD-Na score at listing, mean (SD) | 20.3 (8.6) | 21.2 (8.3) | 19.8 (8.7) | .003 |
| With pLD | 19.9 (7.7) | 20.1 (8.0) | 19.6 (7.5) | .48 |
| Without pLD | 20.5 (9.0) | 22.1 (8.5) | 19.9 (9.2) | .006 |
| MELD-Na score at listing, median (range) | 19 (6-54) | 20 (6-54) | 19 (6-50) | .002 |
| With pLD | 19 (6-50) | 19 (6-50) | 19 (6-47) | .91 |
| Without pLD | 19 (6-54) | 22 (6-54) | 19 (6-50) | < .001 |
| Change in MELD-Na score, mean (SD) | 1.2 (5.8) | 1.3 (6) | 1.1 (5.6) | .24 |
| With pLD | 1.5 (5.9) | 1.1 (5.7) | 1.7 (6.0) | .09 |
| Without pLD | 1.0 (5.7) | 1.5 (6.3) | 0.7 (5.4) | .24 |
| MDRD eGFR, mean (range), mL/min/1.732 | 76.7 (29.4) | 69.2 (28.7) | 80.8 (28.8) | <001 |
| Blood group | ||||
| A | 493 (38) | 174 (38) | 319 (38) | .95 |
| AB | 77 (6) | 29 (6) | 48 (6) | |
| B | 179 (14) | 66 (14) | 113 (14) | |
| O | 540 (42) | 190 (41) | 350 (42) | |
| Type of transplant | ||||
| No transplant | 506 (39) | 188 (41) | 318 (38) | .001 |
| DDLT | 573 (44) | 172 (37) | 401 (48) | |
| LDLT | 210 (16) | 99 (22) | 111 (13) | |
| Time on the waiting list, median (range), mo | 5 (0-74) | 4 (0-74) | 5 (0-67) | .37 |
| Outcome | ||||
| Active listing | 90 (7) | 36 (8) | 54 (7) | .35 |
| Delisted | 197 (15) | 65 (14) | 132 (16) | |
| Death | 219 (17) | 87 (19) | 132 (16) | |
| Transplanted | 783 (61) | 271 (59) | 512 (62) | |
Abbreviations: BMI, body mass index; DDLT, deceased donor liver transplant; LDLT, living donor liver transplant; MDRD eGFR, Modification of Diet in Renal Disease estimated glomerular filtration rate; MELD-Na, Model for End-stage Liver Disease incorporating sodium levels; NA, not applicable; pLD, potential living donor.
a
Calculated as weight in kilograms divided by height in meters squared.