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. 2021 Aug 18;6(11):1–10. doi: 10.1001/jamacardio.2021.3055

Figure 1. Compositional Plaque Changes According to Baseline Plaque Volume and Statin Use.

Figure 1.

Estimated changes in low-attenuation plaque (LAP), fibro-fatty plaque, fibrous plaque, low-density calcium, high-density calcium, and 1K plaque are presented according to baseline plaque volume and statin use. The estimated changes (bold lines) and 95% CIs (shaded areas) are derived from a generalized linear model, including baseline plaque volume, statin use, and the interaction term. The P values for interaction are derived from Table 2. Without statin therapy, increasing trends for all noncalcified and calcified density subgroups are observed, whereas with statin therapy, significant decreases in LAP and fibro-fatty plaque and larger increases in high-density calcium and 1K plaque are observed.