Figure 2. Calcium Densification With Statin Therapy.

Data are restricted to lesions without low-attenuation and fibro-fatty plaque. Estimated changes in overall calcium, low-density calcium, and higher-density calcium according to statin therapy. Estimated changes in plaque volume are shown for the mean baseline plaque volume, the mean of other continuous variables, and the geometric mean of categorical variables. P values represent the interaction between plaque volume and statin use, adjusted for age, sex, diabetes, hypertension, smoking status, body mass index, and computed tomography interval, derived from linear mixed models. HU indicates Hounsfield units.