Figure 3. Coronary Atherosclerosis Progression With or Without Statin Therapy.

Progression of plaque over time in coronary lesions of patients treated with or without statins. For each of the 4 time points, 1 multiplanar reconstruction is provided with 2 cross-sectional views obtained at the same site at baseline and follow-up. A, Statin therapy is associated with the reduction of fibro-fatty (light green) plaque together with densification of the calcification (from low-density calcium [gray] to high-density calcium [purple]). B, Plaque expansion of both noncalcified and calcified plaque is observed. LAP indicates low-attenuation plaque.