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. 2021 Aug 18;6(11):1–10. doi: 10.1001/jamacardio.2021.3055

Table 2. Baseline Plaque Volume and Statin Use Associated With Change in Compositional Volumetric Plaque.

Model^a	Change in compositional volumetric plaque
	Low-attenuation plaque		Fibro-fatty plaque		Fibrous plaque		Low-density calcium		High-density calcium		1K plaque
	Adjusted β coefficient (95% CI)^b	P value	Adjusted β coefficient (95% CI)^b	P value	Adjusted β coefficient (95% CI)^b	P value	Adjusted β coefficient (95% CI)^b	P value	Adjusted β coefficient (95% CI)^b	P value	Adjusted β coefficient (95% CI)^b	P value
Plaque volume at baseline, mm³	0.003 (−0.006 to 0.012)	.47	0.014 (0.003 to 0.026)	.01	0.01 (−0.01 to 0.04)	.19	0.10 (0.09 to 0.12)	<.001	0.04 (0.03 to 0.05)	<.001	0.025 (0.017 to 0.033)	<.001
Statin use, No.	−0.27 (−1.26 to 0.72)	.60	0.09 (−1.15 to 1.33)	.89	−2.51 (−4.79 to −0.24)	.03	0.31 (−1.20 to 1.81)	.69	0.34 (−0.42 to 1.09)	.38	0.03 (−0.71 to 0.77)	.94
Plaque volume at baseline × statin use	−0.02 (−0.03 to −0.01)	.001	−0.03 (−0.04 to −0.02)	<.001	−0.01 (−0.03 to 0.02)	.58	−0.01 (−0.03 to 0.003)	.11	0.02 (0.01 to 0.03)	<.001	0.02 (0.01 to 0.03)	<.001

^{^a}

Generalized linear mixed models with random intercept.

^{^b}

Adjusted for age, sex, diabetes, hypertension, smoking status, body mass index, and computed tomography interval.