Table 1.
Ten-Year Outcomes of Uveal Melanoma Based on The Cancer Genome Atlas (TCGA) Classification in 1001 Cases. Patient demographics
| Patient Demographics | TCGA Class | Total Population | ||||
|---|---|---|---|---|---|---|
|
| ||||||
| A (n=486) [n (%)] | B (n=141) [n (%)] | C (n=260) [n (%)] | D (n=114) [n (%)] | P | (n=1001) [n (%)] | |
| Age | ||||||
| Mean (years) (median, range) | 56.8 (58.0, 10.0 - 90.0) | 52.8 (54.0, 13.0 - 83.0) | 61.1 (62.5, 12.0 - 88.0) | 63.5 (64.0, 28.0 - 94.0) | <0.001 | 58.1 (59.0, 10.0 - 94.0) |
| Sex | ||||||
| Male | 266 (55) | 72 (51) | 121 (47) | 57 (50) | 0.194 | 516 (52) |
| Female | 220 (45) | 69 (49) | 139 (53) | 57 (50) | 485 (48) | |
| Race | ||||||
| Caucasian | 472 (97) | 130 (92) | 251 (97) | 112 (98) | 0.088 | 965 (96) |
| African American | 0 (0) | 2 (1) | 0 (0) | 0 (0) | 2 (<1) | |
| Hispanic | 10 (2) | 3 (2) | 5 (2) | 2 (2) | 20 (2) | |
| Asian | 1 (<1) | 3 (2) | 1 (<1) | 0 (0) | 5 (<1) | |
| Other/unknown | 3 (1) | 3 (2) | 3 (1) | 0 (0) | 9 (1) | |
| Affected eye | ||||||
| Right | 249 (51) | 77 (55) | 143 (55) | 60 (53) | 0.760 | 529 (53) |
| Left | 237 (49) | 64 (45) | 117 (45) | 54 (47) | 472 (47) | |
| Visual Acuity | ||||||
| 20/20 - 20/50 | 389 (80) | 94 (67) | 182 (70) | 74 (65) | 0.001 | 739 (74) |
| 20/60 - 20/200 | 55 (11) | 29 (21) | 53 (20) | 28 (25) | 165 (16) | |
| 20/400 - NLP | 42 (9) | 18 (13) | 25 (10) | 12 (11) | 97 (10) | |
Bold values indicate significant P. TCGA=The Cancer Genome Atlas; NLP=No light perception