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. 2021 Jun 18;69(7):1658–1669. doi: 10.4103/ijo.IJO_1872_20

Table 3.

Grading and Management of Epithelial Ingrowth (Probst and Machat grading)[88]

Grade Signs Location Progression Treatment
1 1-2 cell thick fine growth with a white demarcated line along progressing edge; Difficult to identify on slit-lamp examination Within 2 mm of the flap edge No Not required
2 Thick growth showing discrete cells in the epithelial nest with no demarcation line; Flap edge may be rolled or grey in appearance Within 2 mm of the flap edge Yes Required within 2-3 weeks
3 Several cells thick opaque ingrowth with no demarcation line; The flap may be rolled with whitish-grey appearance; Peripheral confluent haze at the flap edge >2 mm from flap edge Yes Urgently required
4 Aggressive growth with epithelial cells advancing towards the visual axis; Flap melt may be present Threatening/involving visual axis Yes Urgently required