Table 3. Effect of Miniaturized SQ in Liver Function and Lipid Profile among Different Rat Groups.
particulars | control | CCl4 | silymarin | quercetin | SQ | LDMSQ | MDMSQ | HDMSQ |
---|---|---|---|---|---|---|---|---|
ALT (U/L) | 131.2 ± 2.51c | 170.9 ± 6.85a | 136.6 ± 2.17b | 137.5 ± 2.84b | 138.1 ± 3.21b | 129.9 ± 1.62c | 131.8 ± 2.45c | 130.7 ± 3.37c |
AST (U/L) | 130.4 ± 2.26c | 167.5 ± 4.01a | 135.5 ± 2.91b | 136.1 ± 2.34b | 137.0 ± 3.05c | 130.8 ± 3.61c | 132.6 ± 3.47c | 129.1 ± 2.54c |
ALP (U/L) | 188.2 ± 5.06b | 240.2 ± 7.12a | 198.2 ± 4.36b | 200.7 ± 3.29b | 198.0 ± 7.27b | 189.7 ± 5.12b | 184.2 ± 7.15b | 187.5 ± 6.84b |
GGT (U/L) | 8.407 ± 0.68b | 11.430 ± 0.35a | 8.407 ± 0.34b | 8.522 ± 0.35b | 8.812 ± 0.26b | 8.627 ± 0.42b | 8.652 ± 0.68b | 8.603 ± 0.93b |
HDL (mg/dL) | 40.95 ± 7.74a | 28.94 ± 4.47b | 38.94 ± 2.32a | 40.28 ± 3.73a | 39.61 ± 2.54a | 43.64 ± 3.70a | 44.31 ± 1.39a | 45.65 ± 2.47a |
LDL (mg/dL) | 40.73 ± 4.40b | 78.33 ± 3.07a | 59.53 ± 3.90b | 50.13 ± 4.12b | 44.86 ± 2.36b | 43.86 ± 1.83b | 44.93 ± 3.13b | 46.42 ± 2.44b |
total cholesterol (mg/dL) | 166.6 ± 14.6b | 183.3 ± 12.7a | 162.6 ± 10.3b | 165.0 ± 11.4b | 163.3 ± 7.69b | 157.6 ± 10.3b | 156.3 ± 13.0b | 158.0 ± 10.8b |
triacylglycerols (mg/dL) | 124.8 ± 6.56b | 151.4 ± 4.52a | 131.5 ± 6.81b | 128.7 ± 5.42b | 128.7 ± 8.48b | 127.6 ± 6.01b | 124.6 ± 10.1b | 120.0 ± 8.96b |
bilirubin (mg/dL) | 0.725 ± 0.27d | 2.634 ± 0.12a | 1.253 ± 0.06b | 1.356 ± 0.10b | 1.206 ± 0.08b | 1.122 ± 0.07c | 1.136 ± 0.06c | 1.142 ± 0.09c |
total protein (g/dL) | 7.533 ± 0.21b | 4.992 ± 0.98c | 6.662 ± 0.50b | 6.321 ± 0.18b | 6.591 ± 0.38b | 7.871 ± 0.93a | 7.820 ± 0.64a | 7.863 ± 0.36a |
glucose (mg/dL) | 85.82 ± 4.52b | 108.82 ± 4.75a | 89.70 ± 5.62b | 93.52 ± 5.33b | 95.21 ± 4.12b | 87.11 ± 5.10b | 85.88 ± 5.10b | 87.64 ± 4.52b |
albumin (g/dL) | 3.853 ± 0.09a | 2.491 ± 0.10c | 3.091 ± 0.09b | 3.045 ± 0.06b | 3.089 ± 0.12b | 3.215 ± 0.18b | 3.442 ± 0.12b | 3.353 ± 0.16b |
uric acid (mg/dL) | 4.404 ± 0.95b | 7.773 ± 0.73a | 6.073 ± 0.32b | 6.021 ± 0.69b | 6.146 ± 0.60b | 5.712 ± 0.92b | 5.621 ± 0.57b | 5.587 ± 0.65b |
creatinine (mg/dL) | 0.612 ± 0.07b | 1.196 ± 0.05a | 0.912 ± 0.03b | 0.971 ± 0.06b | 0.975 ± 0.06b | 0.880 ± 0.03b | 0.892 ± 0.04b | 0.825 ± 0.05b |