Table 3. Common Side Effects & Recommended Management Strategies for IV Ketamine.

Medications for nausea & vomiting		• Ondansetron prior to infusion/in PACU/Recovery • IV dexamethasone at the start of treatment in situations where patient previously had severe nausea from a ketamine infusion • Scopolamine patch (placed behind the ears) if the other options fail
Medication for headaches		• PO or IV acetaminophen • IV or PO ketorolac 30 mg
Other potential side effects that may arise & may require clinician intervention		• Significant tachycardia (Consider slowing infusion) • Significant hypertension (consider beta blockers or slow infusion) • Increased salivation • Agitation, hallucinations, nightmares