Table 4.
Demographic Characteristics of the Low PWV and High PWV Groups in the NTG Group
| Low PWV (n = 44) | High PWV (n = 59) | ||
|---|---|---|---|
| (PWV < 1400 cm/s) | (PWV ≥ 1400 cm/s) | P Value | |
| Systemic parameters | |||
| Age (years) | 56.3 ± 7.2 | 65.6 ± 8.7 | <0.001 |
| Male (%) | 28 | 27 | 0.072 |
| Body mass index (kg/m2) | 24.3 ± 3.1 | 23.6 ± 2.8 | 0.232 |
| Pulse wave velocity (cm/s) | 1242.0 ± 90.4 | 1758.3 ± 342.8 | <0.001 |
| Hypertension (%) | 12 | 34 | 0.002 |
| Systolic BP (mmHg) | 116.7 ± 11.6 | 136.3 ± 15.7 | <0.001 |
| Diastolic BP (mmHg) | 72.6 ± 8.3 | 80.7 ± 10.2 | <0.001 |
| Mean arterial pressure (mmHg) | 87.3 ± 9.0 | 99.3 ± 11.0 | <0.001 |
| Diabetes (%) | 4 | 18 | 0.009 |
| HbA1c (%) | 5.7 ± 0.8 | 6.2 ± 1.4 | 0.022 |
| Dyslipidemia (%) | 14 | 2 | 0.453 |
| Total cholesterol (mg/dL) | 187.4 ± 37.9 | 168.6 ± 46.2 | 0.030 |
| Triglycerides (mg/dL) | 129.2 ± 91.2 | 126.3 ± 79.4 | 0.860 |
| HDL cholesterol (mg/dL) | 51.9 ± 10.6 | 49.7 ± 12.7 | 0.356 |
| LDL cholesterol (mg/dL) | 111.5 ± 35.4 | 93.5 ± 38.5 | 0.017 |
| Chronic kidney disease (%) | 0 | 9 | 0.007 |
| eGFR (ml/min) | 94.7 ± 14.0 | 81.1 ± 19.4 | <0.001 |
| Uric acid | 5.8 ± 1.6 | 5.3 ± 1.5 | 0.121 |
| Ocular parameters | |||
| Intraocular pressure (mmHg) | 12.9 ± 2.0 | 13.6 ± 1.9 | 0.057 |
| Axial length (mm) | 24.8 ± 1.5 | 24.0 ± 1.3 | 0.008 |
| Spherical equivalent (D) | −2.2 ± 3.0 | −0.8 ± 2.5 | 0.010 |
| Average RNFL thickness (µm) | 78.7 ± 12.2 | 76.4 ± 12.4 | 0.359 |
| Average GCIPL thickness (µm) | 72.7 ± 8.1 | 71.1 ± 8.4 | 0.343 |
| Peripapillary VD (mm−1) | 16.6 ± 1.6 | 15.9 ± 1.5 | 0.036 |
| Macular VD (mm−1) | 16.8 ± 1.7 | 15.3 ± 1.8 | <0.001 |
| Visual field mean deviation (dB) | −4.0 ± 4.7 | −3.4 ± 2.4 | 0.436 |
PWV: pulse wave velocity; NTG: normal-tension glaucoma; BP: blood pressure; HbA1c: hemoglobin A1c; HDL: high-density lipoprotein; LDL: low-density lipoprotein; eGFR: estimated glomerular filtration rate; RNFL: retinal nerve fiber layer; GCIPL: ganglion cell–inner plexiform layer; VD: vessel density.