Table 2.

List of the Proteins That Validated via Multiplex ELISA Assay. Multiplex ELISA was Performed for Nine Proteins to Validate the MS1 Results. Nine Proteins Shown in the Table. Fetuin B Protein was Found not Detectable via the Multiplex ELISA and not Present

Protein name		AMD vs. Control	nvAMD vs. Control	aAMD vs. Control	aAMD vs. nvAMD
IGFBP-2	mean (SD)	0.975492808	1.008362027	1.008362027	1.072410923
	P value*	0.5401	0.7508	0.9629	0.6414
IL-1 R3	mean (SD)	0.535656929	0.498382857	0.695160229	1.394831742
	P value	0.0418	0.1073	0.346	0.25
Clusterin	mean (SD)	1.062251272	0.995116819	1.112383554	1.11784218
	P value	0.0321	0.87	0.0045	0.0016
Serpin A4	mean (SD)	0.980970015	0.928417489	1.09016161	1.174214858
	P value	0.6221	0.0491	0.0414	0.002
CRP	mean (SD)	1.084106393	1.342750368	0.742959842	0.553311963
	P value	0.7869	0.46	0.38	0.1154
RBP-4	mean (SD)	0.798257282	0.970020658	1.24505538	0.82800002
	P value	0.123	0.8399	0.3744	0.2759
Adipsin	mean (SD)	1.013083426	1.064145886	1.046463066	0.983383087
	P value*	0.8514	0.39	0.622	0.844
TF	mean (SD)	0.651255947	0.478581978	0.797364689	0.016
	P value*	0.1437	0.1293	0.5217	1.666098446