TABLE 1.
Univariate and multivariate Cox analysis of PACSIN1 expression and clinical indicators in CGGA dataset.
| Clinical factors | Univariate | p | Multivariate | p | ||||
|---|---|---|---|---|---|---|---|---|
| HR | 95%CI | HR | 95%CI | |||||
| Lower | Upper | Lower | Upper | |||||
| Age | 1.033 | 1.020 | 1.046 | <0.0001 | 1.013 | 1.000 | 1.025 | 0.047 |
| Gender (Male) | 0.935 | 0.709 | 1.232 | 0.631 | — | — | — | — |
| IDH mutation status (Mutant) | 0.355 | 0.268 | 0.470 | <0.0001 | 1.013 | 0.719 | 1.429 | 0.940 |
| 1p/19q status (Non-codel) | 5.887 | 3.608 | 9.606 | <0.0001 | 3.803 | 2.254 | 6.417 | <0.0001 |
| Grade (WHO IV) | 4.758 | 3.536 | 6.402 | <0.0001 | 2.734 | 1.942 | 3.848 | <0.0001 |
| High PACSIN1 expression | 0.555 | 0.475 | 0.649 | <0.0001 | 0.741 | 0.633 | 0.868 | <0.0001 |