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. 2021 Aug 19;22:58. doi: 10.1186/s12865-021-00449-1

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Frequencies of intratumoral Treg and CD39⁺ Treg in relation to tumor microsatellite status. Frequencies of CD39⁺ Treg were determined by flow cytometry in cell suspensions isolated from colon tumors. A Frequencies of Treg among intratumoral CD4⁺ cells in MSS tumors and MSI-H tumors (n = 44). B Frequencies of CD39⁺ Treg among intratumoral Treg in MSS tumor and MSI-H tumors of patients belonging to group I and II (n = 44). Symbols represent individual values and horizontal lines the median. Individual values are color-coded in red (group I) and blue (group II)