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. 2021 Aug 19;27:91. doi: 10.1186/s10020-021-00355-7

Fig. 7.

Fig. 7

The expression of NLRP3 correlates positively with METTL14 and IGF2BP2 and negatively with miR-26a-5p. A qRT-PCR analysis of METTL14, miR-26a-5p, NLRP3, and IGF2BP2 in N-HNP tissues (n = 10) and D-HNP tissues (n = 20). B Pearson correlation analysis among METTL14, miR-26a-5p, NLRP3, and IGF2BP2 level in 20 cases of D-HNP tissues. C Schematic representation of the regulation of HNPC inflammation and pyroptosis by hucMSC-secreted exosomal miR-26a-5p/METTL14/NLRP3/caspase-1. ***P < 0.001