Table 1.
Patient characteristics
| All patients N = 1212 | Patients with known CAD N = 693 | Patients with suspected CAD N = 519 | *P-value | |
|---|---|---|---|---|
| Clinical variables | ||||
| Age, years | 69 ± 10 | 69 ± 10 | 68 ± 11 | 0.37 |
| Male | 921 (76%) | 554 (80%) | 367 (71%) | < 0.005 |
| BMI, kg/m2 | 24 ± 3 | 24 ± 3 | 24 ± 4 | 0.49 |
| Hypertension | 823 (68%) | 483 (70%) | 340 (66%) | 0.13 |
| Dyslipidemia | 821 (68%) | 488 (70%) | 333 (64%) | 0.021 |
| Diabetes mellitus | 366 (30%) | 229 (33%) | 137 (26%) | 0.012 |
| Current smoking | 79 (7%) | 55 (8%) | 24 (5%) | 0.021 |
| Blood test | ||||
| HbA1c, % | 6.0 ± 0.8 | 6.1 ± 0.9 | 5.9 ± 0.7 | 0.005 |
| LDL cholesterol | 99 ± 28 | 94 ± 27 | 107 ± 30 | < 0.001 |
| eGFR | 66 ± 16 | 67 ± 16 | 66 ± 15 | 0.42 |
| CMR variables | ||||
| LVEDV, mL | 131 ± 46 | 128 ± 42 | 134 ± 51 | 0.053 |
| LVESV, mL | 57 ± 37 | 55 ± 33 | 59 ± 42 | 0.24 |
| LV mass, g | 95 ± 34 | 92 ± 36 | 99 ± 31 | < 0.001 |
| LVEF, % | 60 ± 12 | 60 ± 12 | 59 ± 12 | 0.84 |
| Presence of LGE | 591 (49%) | 439 (63%) | 152 (29%) | < 0.001 |
| LGE, % | 7.9 ± 9.0 | 9.6 ± 9.6 | 5.9 ± 7.7 | < 0.001 |
| Presence of ischemia | 516 (43%) | 195 (28%) | 321 (62%) | 0.002 |
| > 10% ischemia | 258 (21%) | 175 (25%) | 83 (16%) | < 0.001 |
Data are expressed as mean ± SD or number (%)
*P-value represents significance of difference between patients with known CAD and suspected CAD
BMI body mass index, CAD coronary artery disease, CFR coronary flow reserve, CMR cardiac magnetic resonance, eGFR estimated glomerular filtration rate, LDL low-density lipoprotein, LGE late gadolinium enhancement, LV left ventricular, LVEDV left ventricular end-diastolic volume, LVEF left ventricular ejection fraction, LVESV left ventricular end-systolic volume, MACE major adverse cardiac events