Table 2.

Comparison of coronary sinus blood flow and CFR

Patients with known CAD	All patients N = 693	Patients without MACE N = 648	Patients with MACE N = 45	*P-value
CSBF at rest (mL/min)	86.7 ± 32.9	84.7 ± 30.9	114.7 ± 44.9	< 0.001
CSBF during ATP infusion (mL/min)	236.4 ± 87.4**	235.8 ± 88.7**	245.3 ± 66.5**	0.47
ΔCSBF (mL/min)	149.7 ± 72.7	151.1 ± 73.8	130.6 ± 50.9	0.068
Coronary flow reserve	2.84 ± 0.91	2.89 ± 0.92	2.27 ± 0.60	< 0.001

Patients with suspected CAD	All patients N = 519	Patients without MACE N = 472	Patients with MACE N = 47	*P-value
CSBF at rest (mL/min)	89.8 ± 37.8	86.6 ± 36.7	122.2 ± 33.3	< 0.001
CSBF during ATP infusion (mL/min)	242.4 ± 87.4**	241.6 ± 90.3**	250.2 ± 48.5**	0.52
ΔCSBF (mL/min)	152.6 ± 70.1	155.1 ± 72.1	127.9 ± 39.2	0.011
Coronary flow reserve	2.85 ± 0.84	2.93 ± 0.84	2.10 ± 0.40	< 0.001

Data are expressed as mean ± SD or number (%)

*P-values represent the difference between patients with and without MACE. **P < 0.05 vs. CSBF at rest

ΔCSBF = CSBF during ATP infusion–CSBF at rest

Coronary flow reserve = CSBF during ATP infusion / CSBF at rest × 100

ATP adenosine triphosphate, CSBF coronary sinus blood flow, CFR coronary flow reserve, MACE major adverse cardiac events, SD standard deviation