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. 2021 Jul 25;17(12):3118–3132. doi: 10.7150/ijbs.59195

Figure 3.

Figure 3

The knockdown of Sp1 inhibited TGF-β1-induced ECM expression. (A-C) qRT-PCR, western blotting and densitometric analyses of Sp1 expression in BUMPT cells following the transfection of Sp1 siRNA. (D-E) qRT-PCR analysis of the mRNA expression levels of CoL-I and Fn in TGF-β1-stimulated BUMPT cells following transfection with Sp1 siRNA. (F-G) Western blotting and densitometric analyses of CoL-I and Fn expression level in TGF-β1-stimulated BUMPT cells following Sp1 siRNA transfection. *P<0.05, #P<0.05; data are presented as the mean ±SEM (n=3).