Table 5.
Functional characterization of H19 in breast cancer.
Tumor types | Expression | Role | Function role | miRNAs | Related genes | References |
---|---|---|---|---|---|---|
Breast cancer | upregulation | oncogene | proliferation, migration, invasion, and cell cycle | / | TNFAIP8 | 114 |
Breast cancer | upregulation | oncogene | clonogenicity, migration, and mammosphere-forming ability | let-7 | LIN28 | 116 |
Breast cancer | upregulation | oncogene | autophagy and EMT | let-7 | LIN28 | 117 |
Breast cancer | upregulation | oncogene | EMT | miR-200b/c and let 7b | GIT2 and CYTH3 | 118 |
Breast cancer | upregulation | oncogene | proliferation and invasion | miR-152 | DNMT1 | 119 |
Breast cancer | upregulation | oncogene | viability | miR-675-5p | CBL | 120 |
Breast cancer | upregulation | oncogene | migration and invasion | miR-93-5p | STAT3 | 121 |
Breast cancer | upregulation | oncogene | proliferation, migration, invasion, cell cycle, EMT, and apoptosis | miR-138 | SOX4 | 122 |
Breast cancer | upregulation | oncogene | proliferation, metastasis, invasion, EMT, and apoptosis | miR-340-3p | YWHAZ | 123 |
Breast cancer | upregulation | oncogene | proliferation, migration, invasion, and apoptosis | miR-491-5p | ZNF703 | 124 |
Breast cancer | upregulation | oncogene | proliferation, migration, invasion, and apoptosis | miR-130a-3p | SATB1 | 125 |